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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v10i4.755</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-195</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕОТЛОЖНЫЕ СОСТОЯНИЯ У ДЕТЕЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EMERGENCY CONDITIONS IN CHILDREN</subject></subj-group></article-categories><title-group><article-title>ГЕПАТОБИЛИАРНЫЕ ОСЛОЖНЕНИЯ ПАРЕНТЕРАЛЬНОГО ПИТАНИЯ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>HEPATOBILIARY COMPLICATIONS OF PARENTERAL NUTRITION IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тепаев</surname><given-names>Р. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Tepaev</surname><given-names>R. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, главный научный сотрудник отделения анестезиологии-реанимации Научного центра здоровья детей РАМН, профессор кафедры педиатрии с курсом детской ревматологии Первого Московского государственного медицинского университета им. И.М. Сеченова</p></bio><bio xml:lang="en"><p>PhD, chief research scientist at the anesthesiology-resuscitation department of the Scientific Center of Children’s Health, Professor at the pediatrics department with a course of pediatric rheumatology at the First Sechenov Moscow State Medical University</p></bio><email xlink:type="simple">rtepaev@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кирьянова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiryanova</surname><given-names>A. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильичёва</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyicheva</surname><given-names>E. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва, Российская Федерация&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Center of Children’s Health, Moscow, Russian Federation&#13;
First Sechenov Moscow State Medical University, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Center of Children’s Health, Moscow, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>14</day><month>08</month><year>2013</year></pub-date><volume>10</volume><issue>4</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>53</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тепаев Р.Ф., Кирьянова А.Н., Ильичёва Е.И., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Тепаев Р.Ф., Кирьянова А.Н., Ильичёва Е.И.</copyright-holder><copyright-holder xml:lang="en">Tepaev R.F., Kiryanova A.N., Ilyicheva E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/195">https://www.pedpharma.ru/jour/article/view/195</self-uri><abstract/><trans-abstract xml:lang="en"><p>Parenteral nutrition allows adequately providing children’s bodies with amino acids, carbohydrates, fats and energy required to maintain the baseline energy level and correct the preceding nutritive deficiency. Long-term parenteral nutrition is associated with hepatobiliary complications of varying severity – from transitory complications to lethal ones, caused by cholestasis. The article presents modern data on diagnostics, prevention and treatment of hepatobiliary complications of parenteral nutrition in children.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>холестаз</kwd><kwd>заболевание печени</kwd><kwd>ассоциированное с парентеральным питанием</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>cholestasis</kwd><kwd>liver disease</kwd><kwd>associated with parenteral nutrition</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lauriti G., Zani A., Aufieri R., Cananzi M. et al. 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