ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v17i6.2205ppharm-1925Research ArticleКЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИCLINICAL RECOMMENDATIONSПрименение аминокислотных смесей при пищевой аллергииAmino acid formulas in patients with food allergyhttps://orcid.org/0000-0003-3987-8112БарановА. А.BaranovAlexander A.

Москва

Moscow

https://orcid.org/0000-0002-2209-7531Намазова-БарановаЛ. С.Namazova-BaranovaLeyla S.

Намазова-Баранова Лейла Сеймуровна, доктор медицинских наук, профессор, академик РАН, заведующая кафедрой факультетской педиатрии педиатрического факультета ФГБОУ ВО «РНИМУ им. Н.И. Пирогова» Минздрава России, руководитель НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ, президент Союза педиатров России

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info@pediatr-russia.ruhttps://orcid.org/0000-0002-8023-2543АлексееваА. А.AlexeevaAnna A.

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https://orcid.org/0000-0002-8232-8936АмбарчянЭ. Т.AmbarchianEduard T.

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https://orcid.org/0000-0002-0415-9516АсламазянЛ. К.AslamazyanLianna K.

Москва

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https://orcid.org/0000-0002-7691-4584АстафьеваН. Г.AstafievaNatalia G.

Саратов

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https://orcid.org/0000-0002-2290-0013БалыковаЛ. А.BalykovaLarisa A.

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https://orcid.org/0000-0002-8717-2539БеляеваИ. А.BelyaevaIrina A.

Москва

Moscow

БулгаковаВ. А.BulgakovaVilya A.

Москва

Moscow

https://orcid.org/0000-0002-5274-4699ВахловаИ. В.VakhlovaIrina V.

Екатеринбург

Ekaterinburg

https://orcid.org/0000-0001-8320-2027ВашакмадзеН. Д.VashakmadzeNato D.

Москва

Moscow

https://orcid.org/0000-0001-7398-0562ВишнёваЕ. А.VishnevaElena A.

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ГетияЕ. Г.GetiyaEkaterina G.

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https://orcid.org/0000-0002-3556-969XИльинаН. И.Il'inaNatalia I.

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https://orcid.org/0000-0002-8936-3590КайтуковаЕ. В.KaytukovaElena V.

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https://orcid.org/0000-0001-8184-9230КамалтыноваЕ. М.KamaltynovaElena M.

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https://orcid.org/0000-0002-8540-3858КаркашадзеГ. А.KarkashadzeGeorgiy A.

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https://orcid.org/0000-0002-5250-7351КовтунО. П.KovtunOlga P.

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КомароваЕ. В.KomarovaElena V.

Москва

Moscow

https://orcid.org/0000-0002-7447-0625КуличенкоТ. В.KulichenkoTatiana V.

Москва

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https://orcid.org/0000-0003-3250-0694КурбачеваО. М.KurbachevaOksana M.

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https://orcid.org/0000-0002-2460-7718ЛевинаЮ. Г.LevinaYuliya G.

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https://orcid.org/0000-0003-2252-8570МурашкинН. Н.MurashkinNikolay N.

Москва

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НестероваЮ. В.NesterovaYuliya V.

Москва

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НовикГ. А.NovikGennady A.

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Saint Petersburg

ПискуноваС. Г.PiskunovaSvetlana G.

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ПоповаЛ. Ю.PopovaLarisa Yu.

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Orenburg

https://orcid.org/0000-0003-4680-2925ПриваловаТ. Е.PrivalovaTatyana E.

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https://orcid.org/0000-0002-3678-7939СелимзяноваЛ. Р.SelimzyanovaLilia R.

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СергиенкоН. С.SergienkoNatalia S.

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Moscow

https://orcid.org/0000-0002-4692-4802СеребряковаЕ. Н.SerebryakovaElena N.

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СтасийЕ. Д.StasiyEkaterina D.

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ТкаченкоМ. А.TkachenkoMikhail A.

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Saint Petersburg

https://orcid.org/0000-0002-4955-0121ТуртиТ. В.TurtiTatiana V.

Москва

Moscow

https://orcid.org/0000-0002-3167-082XУстиноваН. В.UstinovaNatalia V.

Москва

Moscow

https://orcid.org/0000-0002-7130-9609ФедороваО. С.FedorovaOlga S.

Томск

Tomsk

https://orcid.org/0000-0002-5083-6637ФоминаД. С.FominaDaria S.

Москва

Moscow

https://orcid.org/0000-0003-3502-1912ФугольД. С.FugolDenis S.

Барнаул

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https://orcid.org/0000-0002-3598-9600ЧемакинаД. С.ChemakinaDaria S.

Москва

Moscow

ШепелеваИ. М.ShepelevaIrina M.

Москва

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https://orcid.org/0000-0003-0317-2425ЭфендиеваК. Е.EfendievaKamilla E.

Москва

Moscow

НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет)РоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Sechenov First Moscow State Medical UniversityRussian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Белгородский государственный национальный исследовательский университетРоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; Belgorod National Research UniversityRussian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФРоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Russian FederationНациональный медицинский исследовательский Центр Здоровья ДетейРоссияNational Medical Research Center of Children’s HealthRussian FederationСаратовский государственный медицинский университет им. В.И. РазумовскогоРоссияSaratov State Medical University named after V.I. RazumovskyRussian FederationМордовский государственный университет им. Н.П. ОгарёваРоссияN. P. Ogarev Mordovia State UniversityRussian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Морозовская детская городская клиническая больница, МоскваРоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; Morozovskaya Children's City HospitalRussian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Национальный медицинский исследовательский Центр Здоровья ДетейРоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; National Medical Research Center of Children’s HealthRussian FederationУральский государственный медицинский университетРоссияUral State Medical UniversityRussian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. ПироговаРоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityRussian FederationАссоциация педиатров ГрузииГрузияGeorgian Paediatric AssociationGeorgiaРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова; Государственный научный центр Институт иммунологииРоссияPirogov Russian National Research Medical University; National Research Center “Institute of Immunology”Russian FederationСибирский государственный медицинский университетРоссияSiberian State Medical UniversityRussian FederationРоссийский национальный исследовательский медицинский университет им. Н.И. ПироговаРоссияPirogov Russian National Research Medical UniversityRussian FederationГосударственный научный центр Институт иммунологииРоссияNational Research Center “Institute of Immunology”Russian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет); Национальный медицинский исследовательский Центр Здоровья Детей; Центральная государственная медицинская академия Управления делами Президента Российской ФедерацииРоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Sechenov First Moscow State Medical University; National Medical Research Center of Children’s Health; Central State Medical Academy of Department of Presidential AffairsRussian FederationСанкт-Петербургский государственный педиатрический медицинский университетРоссияSaint Petersburg State Pediatric Medical UniversityRussian FederationОбластная детская клиническая больницаРоссияOblast Children's Clinical HospitalRussian FederationОренбургский государственный медицинский университетРоссияOrenburg State Medical UniversityRussian FederationЮжно-Уральский государственный медицинский университет» Минздрава РоссииРоссияSouth Ural State Medical UniversityRussian FederationГосударственный университет медицины и фармации им. Николая Тестемицану; Институт матери и ребенкаМолдоваNicolae Testemitanu State University of Medicine and Pharmacy; Mother and Child InstituteMoldova, Republic ofНИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Детская городская клиническая больница № 9 имени Г.Н. Сперанского; Центр аллергологии и иммунологии ГБУЗ «Городская клиническая больница № 52 Департамента здравоохранения города Москвы»РоссияResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; The Research Institute of Health Care and Medical Management of the Moscow Health Care Department; G.N. Speransky Children’s City Hospital №9Russian Federationервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет); Центр аллергологии и иммунологии ГБУЗ «Городская клиническая больница № 52 Департамента здравоохранения города Москвы»РоссияSechenov First Moscow State Medical University; Allergology and Immunology Centre of City Clinical Hospital №52 of the Moscow Health Care DepartmentRussian FederationАлтайский государственный медицинский университетРоссияAltai State Medical UniversityRussian FederationСоюз педиатров РоссииРоссияThe Union of pediatricians of RussiaRussian Federation202027012021176536546Copyright © Баранов А.А., Намазова-Баранова Л.С., Алексеева А.А., Амбарчян Э.Т., Асламазян Л.К., Астафьева Н.Г., Балыкова Л.А., Беляева И.А., Булгакова В.А., Вахлова И.В., Вашакмадзе Н.Д., Вишнёва Е.А., Гетия Е.Г., Ильина Н.И., Кайтукова Е.В., Камалтынова Е.М., Каркашадзе Г.А., Ковтун О.П., Комарова Е.В., Куличенко Т.В., Курбачева О.М., Левина Ю.Г., Макарова С.Г., Мурашкин Н.Н., Нестерова Ю.В., Новик Г.А., Пискунова С.Г., Попова Л.Ю., Привалова Т.Е., Селимзянова Л.Р., Сергиенко Н.С., Серебрякова Е.Н., Стасий Е.Д., Ткаченко М.А., Турти Т.В., Устинова Н.В., Федорова О.С., Фомина Д.С., Фуголь Д.С., Чемакина Д.С., Шепелева И.М., Эфендиева К.Е., 20212021Баранов А.А., Намазова-Баранова Л.С., Алексеева А.А., Амбарчян Э.Т., Асламазян Л.К., Астафьева Н.Г., Балыкова Л.А., Беляева И.А., Булгакова В.А., Вахлова И.В., Вашакмадзе Н.Д., Вишнёва Е.А., Гетия Е.Г., Ильина Н.И., Кайтукова Е.В., Камалтынова Е.М., Каркашадзе Г.А., Ковтун О.П., Комарова Е.В., Куличенко Т.В., Курбачева О.М., Левина Ю.Г., Макарова С.Г., Мурашкин Н.Н., Нестерова Ю.В., Новик Г.А., Пискунова С.Г., Попова Л.Ю., Привалова Т.Е., Селимзянова Л.Р., Сергиенко Н.С., Серебрякова Е.Н., Стасий Е.Д., Ткаченко М.А., Турти Т.В., Устинова Н.В., Федорова О.С., Фомина Д.С., Фуголь Д.С., Чемакина Д.С., Шепелева И.М., Эфендиева К.Е.Baranov A.A., Namazova-Baranova L.S., Alexeeva A.A., Ambarchian E.T., Aslamazyan L.K., Astafieva N.G., Balykova L.A., Belyaeva I.A., Bulgakova V.A., Vakhlova I.V., Vashakmadze N.D., Vishneva E.A., Getiya E.G., Il'ina N.I., Kaytukova E.V., Kamaltynova E.M., Karkashadze G.A., Kovtun O.P., Komarova E.V., Kulichenko T.V., Kurbacheva O.M., Levina Y.G., Makarova S.G., Murashkin N.N., Nesterova Y.V., Novik G.A., Piskunova S.G., Popova L.Y., Privalova T.E., Selimzyanova L.R., Sergienko N.S., Serebryakova E.N., Stasiy E.D., Tkachenko M.A., Turti T.V., Ustinova N.V., Fedorova O.S., Fomina D.S., Fugol D.S., Chemakina D.S., Shepeleva I.M., Efendieva K.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/1925

В статье приводятся современные подходы к использованию сбалансированных детских смесей, которые предназначены для вскармливания и коррекции рациона детей, страдающих различными формами пищевой аллергии. Рекомендации разработаны на основании всех доступных на сегодняшний день доказательств эффективности, безопасности и полезности использования такой инновационной медицинской технологии, как специализированные аминокислотные смеси. Данная формула является таргетным медицинским вмешательством при пищевой аллергии и подтвержденной аллергии к белкам коровьего молока, особенно для пациентов со сниженными показателями физического развития, в том числе темпов роста. Материал основан на методическом руководстве по применению аминокислотных смесей, ранее разработанном экспертами-специалистами Союза педиатров России в 2020 г.

The article presents modern approaches to the use of balanced formulas for nutrition and diet correction in children with various forms of food allergies. The guidelines are based on all available up to date evidence on the efficacy, safety and utility of using such innovative medical technology as specialized amino acid formulas. This formula is the targeted medical intervention for food allergies and confirmed cow's milk protein allergy, and particularly for patients with reduced physical growth and development (growth rates included). The material is based on methodological guidelines on the amino acid formulas usage previously developed by specialist experts of the Union of pediatricians of Russia in 2020.

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The authors declare that there are no conflicts of interest present.