References

ppharm

Педиатрическая фармакология

Pediatric pharmacology

1727-57762500-3089

Издательство «ПедиатрЪ»

10.15690/pf.v10i4.752

ppharm-192

Research Article

ВАКЦИНАЦИЯ В СОВРЕМЕННОМ МИРЕ

VACCINATION

ВАКЦИНАЦИЯ НЕДОНОШЕННЫХ И МАЛОВЕСНЫХ ДЕТЕЙ

VACCINATION OF PREMATURE/LOW-BIRTH-WEIGHT CHILDREN

Таточенко

В. К.

Tatochenko

V. K.

доктор медицинских наук, профессор, главный научный сотрудник НЦЗД РАМН

PhD, Professor, chief research fellow of the RAMS SCCH

tatochenko@nczd.ru

Научный центр здоровья детей РАМН, Москва, Российская ФедерацияРоссияScientific Center of Children’s Health, MoscowRussian Federation

2013

14082013

104

Педиатрическая фармакология

3036

2013

Таточенко В.К.

Tatochenko V.K.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.pedpharma.ru/jour/article/view/192

The article is dedicated to vaccination of premature/low-birth-weight children. This is an extremely topical issue as these children are the most susceptible to infectious diseases, including controlled diseases; however, specialists are reluctant to vaccinate them due to possible unfavorable responses of premature bodies to the introduction of an immunotropic agent. The authors present peculiarities of immune response of premature infants, of the T-cell level in particular, which are to be taken into account during vaccination. Special attention is given to the safety of vaccines – risk of development of apneic episodes with/without bradycardia, their influence on the frequency of obstructive episodes and effect of simultaneous introduction of several vaccines on body. Moreover, the article sets forward issues of immunogenicity and reactogenicity of various vaccines when administered to low-birth-weight children.

вакцинацияиммуногенностьреактогенностьбезопасностьнедоношенные и маловесные дети

vaccinationimmunogenicityreactogenicitysafetypremature and low-birth-weight children

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The authors declare that there are no conflicts of interest present.