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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v16i6.2071</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-1788</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RECOMMENDATIONS</subject></subj-group></article-categories><title-group><article-title>Современные подходы к ведению детей с острым бронхиолитом</article-title><trans-title-group xml:lang="en"><trans-title>Modern Approaches in management of Children with Acute Bronchiolitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3987-8112</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>Alexander A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2209-7531</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova-Baranova</surname><given-names>Leyla S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8085-4513</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таточенко</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Tatochenko</surname><given-names>Vladimir K.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7780-6737</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давыдова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Davydova</surname><given-names>Irina V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6474-6766</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакрадзе</surname><given-names>М. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakradze</surname><given-names>Maia D.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7447-0625</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куличенко</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulichenko</surname><given-names>Tatiana V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Контактная информация: Куличенко Татьяна Владимировна, доктор медицинских наук, профессор РАН, член Союза педиатров России, главный внештатный детский специалист-педиатр Министерства здравоохранения Российской Федерации в Центральном федеральном округе (по согласованию), врач-педиатр государственного бюджетного учреждения «Морозовская детская клиническая больница Департамента здравоохранения города Москвы»</p><p>Адрес: 119049, Москва, 4-й Добрынинский пер., д. 1/9, тел.: +7 (495) 959-88-03</p></bio><bio xml:lang="en"/><email xlink:type="simple">tkulichenko@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7398-0562</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вишнёва</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vishnyova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3678-7939</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селимзянова</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Selimzyanova</surname><given-names>Liliya R.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полякова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakova</surname><given-names>Anastasia S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артёмова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Artemova</surname><given-names>Inga V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт педиатрии и охраны здоровья детей ЦКБ РАН<country>Россия</country></aff><aff xml:lang="en">Central Clinical Hospital of the Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научно-исследовательский институт педиатрии и охраны здоровья детей ЦКБ РАН; &#13;
Российский национальный исследовательский медицинский университет им. Н.И. Пирогова<country>Россия</country></aff><aff xml:lang="en">Central Clinical Hospital of the Russian Academy of Sciences; &#13;
Pirogov Russian National Research Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Национальный медицинский исследовательский центр здоровья детей<country>Россия</country></aff><aff xml:lang="en">National Medical Research Center of Children’s Health<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова<country>Россия</country></aff><aff xml:lang="en">Pirogov Russian National Research Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">Научно-исследовательский институт педиатрии и охраны здоровья детей ЦКБ РАН; &#13;
Первый Московский государственный медицинский университет имени И. М. Сеченова (Сеченовский Университет)<country>Россия</country></aff><aff xml:lang="en">Central Clinical Hospital of the Russian Academy of Sciences; &#13;
Sechenov First Moscow State Medical University (Sechenov University)<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>21</day><month>02</month><year>2020</year></pub-date><volume>16</volume><issue>6</issue><fpage>339</fpage><lpage>348</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баранов А.А., Намазова-Баранова Л.С., Таточенко В.К., Давыдова И.В., Бакрадзе М.Д., Куличенко Т.В., Вишнёва И.В., Селимзянова Л.Р., Полякова А.С., Артёмова И.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Баранов А.А., Намазова-Баранова Л.С., Таточенко В.К., Давыдова И.В., Бакрадзе М.Д., Куличенко Т.В., Вишнёва И.В., Селимзянова Л.Р., Полякова А.С., Артёмова И.В.</copyright-holder><copyright-holder xml:lang="en">Baranov A.A., Namazova-Baranova L.S., Tatochenko V.K., Davydova I.V., Bakradze M.D., Kulichenko T.V., Vishnyova E.V., Selimzyanova L.R., Polyakova A.S., Artemova I.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/1788">https://www.pedpharma.ru/jour/article/view/1788</self-uri><abstract><p>Экспертами Союза педиатров России разработаны актуальные методические рекомендации по оказанию медицинской помощи детям с острым бронхиолитом. Ежегодно в мире регистрируется около 150 млн случаев бронхиолита (11 заболевших на 100 детей грудного возраста), 7–13 % из которых требуют стационарного лечения и 1–3 % — госпитализации в отделение интенсивной терапии. Респираторно-синцитиальную вирусную инфекцию переносят практически все дети в первые 2 года жизни (90 %), однако лишь приблизительно в 20 % случаев у них развивается бронхиолит, что обусловлено различными факторами. В статье подробно освещены вопросы эпидемиологии, патогенеза, дифференциальной диагностики, лечения, основанные на принципах доказательности.</p></abstract><trans-abstract xml:lang="en"><p>The experts of the Union of Pediatricians of Russia have developed up-to-date clinical guidelines on management of children with acute bronchiolitis. Around 150 million cases of bronchiolitis (11 cases per 100 infants) are registered annually, 7–13 % of all cases require hospital treatment and 1–3 % require management in intensive care unit. Almost all children of the age under 2 years old (90 %) undergone respiratory syncytial viral infection. In 20 % of them they have bronchiolitis due to various factors. This article covers the issues of epidemiology, pathogenesis, differential diagnostics, treatment based on the principles of evidence in detail.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый бронхиолит</kwd><kwd>респираторно-синцитиальная вирусная инфекция</kwd><kwd>дыхательная недостаточность</kwd><kwd>профилактика</kwd><kwd>паливизумаб</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute bronchiolitis</kwd><kwd>respiratory syncytial viral infection</kwd><kwd>respiratory failure</kwd><kwd>prevention</kwd><kwd>palivizumab</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Классификация клинических форм бронхолегочных заболеваний у детей. — М.: Российское респираторное общество, 2009. — 18 с. 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