ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v16i4.2054ppharm-1766Research ArticleВ ПРАКТИКУ ПЕДИАТРАFor Pediatricians' PracticeОсобенности формирования эпидермального барьера и применение эмолентов у недоношенных и детей раннего возрастаFeatures of the Formation of the Epidermal Barrier and the Use of Emollients in Premature and Young Childrenhttps://orcid.org/0000-0003-2252-8570МурашкинН. Н.MurashkinNikolay N.

Контактная информация: Мурашкин Николай Николаевич, доктор медицинских наук, профессор, заведующий отделением дерматологии с группой лазерной хирургии ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России

m_nn2001@mail.ruhttps://orcid.org/0000-0002-0081-0981ИвановР. А.IvanovRoman A.https://orcid.org/0000-0001-6884-5171СавеловаА. А.SavelovaA. A.https://orcid.org/0000-0001-9777-0156ФедоровД. В.FedorovD. V.https://orcid.org/0000-0002-0858-8780ОпрятинЛ. А.OpryatinLeonid A.https://orcid.org/0000-0002-4022-5592АхмадВ.AhmadW.Национальный медицинский исследовательский центр здоровья детей; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); Центральная государственная медицинская академия Управления делами Президента Российской ФедерацииРоссияNational Medical Research Center for Children’s Health; I.M. Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of the Administrative Department of the President of the Russian FederationRussian FederationНациональный медицинский исследовательский центр здоровья детейРоссияNational Medical Research Center for Children’s HealthRussian FederationКабардино-Балкарский государственный университет им. Х.М. БербековаРоссияKabardino-Balkarian State University named after H.M. BerbekovRussian Federation201925122019164241247Copyright © Мурашкин Н.Н., Иванов Р.А., Савелова А.А., Федоров Д.В., Опрятин Л.А., Ахмад В., 20192019Мурашкин Н.Н., Иванов Р.А., Савелова А.А., Федоров Д.В., Опрятин Л.А., Ахмад В.Murashkin N.N., Ivanov R.A., Savelova A.A., Fedorov D.V., Opryatin L.A., Ahmad W.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/1766

В статье представлены современные данные об особенностях строения кожи и формирования эпидермального барьера у недоношенных и детей раннего возраста. Приведены сведения, касающиеся изменений свойств кожного покрова — микрорельефа, гидратации, трансэпидермальной потери воды, кислотности, содержания естественного увлажняющего фактора, секреции кожного сала. Также уделено внимание роли сыровидной смазки в образовании зрелого эпидермального барьера и приведены данные об использовании смягчающих/увлажняющих средств.

The article presents modern data on the features of the structure of the skin and the formation of the epidermal barrier in premature and young children. Information is given regarding changes in the properties of the skin: microrelief, hydration, transepidermal water loss, acidity, content of the natural moisturizing factor, and sebum secretion. Attention is also paid to the role of vernix caseosa in the formation of a mature epidermal barrier and data on the use of emollients are provided.

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The authors declare that there are no conflicts of interest present.