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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v10i5.817</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-169</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВАКЦИНАЦИЯ В СОВРЕМЕННОМ МИРЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>VACCINATION</subject></subj-group></article-categories><title-group><article-title>РОТАВИРУСНАЯ ИНФЕКЦИЯ. КАК ДЕЙСТВИТЕЛЬНО ЗАЩИТИТЬ ДЕТЕЙ ОТ ТЯЖЕЛЫХ ГАСТРОЭНТЕРИТОВ?</article-title><trans-title-group xml:lang="en"><trans-title>ROTAVIRUS INFECTION. HOW TO REALLY PROTECT CHILDREN FROM SEVERE GASTROENTERITIS?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гречуха</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grechukha</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, старший научный сотрудник, врач-иммунолог отделения вакцинопрофилактики детей с отклонениями в состоянии здоровья КДЦ «НЦЗД» РАМН</p></bio><bio xml:lang="en"><p>MD, senior research scientist, immunologist of the vaccinal prevention department for children with health deviations of the SCCH</p></bio><email xlink:type="simple">Grechukha@nczd.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галицкая</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Galitskaya</surname><given-names>M. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайворонская</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gayvoronskaya</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova-Baranova</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва<country>Россия</country></aff><aff xml:lang="en">Scientific Center of Children’s Health, Moscow<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва, Российская Федерация&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация&#13;
Российский национальный исследовательский медицинский университет имени Н.И. Пирогова,&#13;
Москва, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Scientific Center of Children’s Health, Moscow, Russian Federation&#13;
First Sechenov Moscow State Medical University, Russian Federation&#13;
Pirogov Russian National Medical Research University, Moscow, Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2013</year></pub-date><volume>10</volume><issue>5</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>14</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гречуха Т.А., Галицкая М.Г., Гайворонская А.Г., Намазова-Баранова Л.С., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Гречуха Т.А., Галицкая М.Г., Гайворонская А.Г., Намазова-Баранова Л.С.</copyright-holder><copyright-holder xml:lang="en">Grechukha T.A., Galitskaya M.G., Gayvoronskaya A.G., Namazova-Baranova L.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/169">https://www.pedpharma.ru/jour/article/view/169</self-uri><abstract/><trans-abstract xml:lang="en"><p>According to the statistics of the recent 5 years, the share of rotavirus gastroenterites is 44-47% of all acute intestinal infections in children under 5 years of age in the Russian Federation. Up to 5% of mortality rate in children under 5 years of age is connected with rotavirus gastroenteritis. Rotavirus gastroenteritis takes an especially severe course in children of 6-24 months of age. The only reliable method of preventing this infection is vaccination. The authors present information on the rotavirus strains dominant in Russia and abroad, efficacy and safety of immunization with a pentavalent vaccine and the recommended schemes of its administration. This vaccine is registered in the Russian Federation; it is to be first used in the nearest future.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ротавирус</kwd><kwd>штаммы</kwd><kwd>дети раннего возраста</kwd><kwd>вакцинопрофилактика</kwd><kwd>эффективность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rotavirus</kwd><kwd>strains</kwd><kwd>infants</kwd><kwd>vaccinal prevention</kwd><kwd>efficacy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Arvin A. M., Greenberg H. B. Virology. 2006; 344: 240–249.</mixed-citation><mixed-citation xml:lang="en">Arvin A. M., Greenberg H. B. Virology. 2006; 344: 240–249.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Centers for disease control and Prevention. 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