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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v15i6.1981</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-1678</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RECOMMENDATIONS</subject></subj-group></article-categories><title-group><article-title>Желудочковая экстрасистолия у детей</article-title><trans-title-group xml:lang="en"><trans-title>Premature Ventricular Contraction in Children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3987-8112</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>Alexander A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васичкина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasichkina</surname><given-names>Elena S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васичкина Елена Сергеевна, д.м.н., профессор кафедры педиатрии им. проф. И.М. Воронцова, руководитель НИЛ детской аритмологии </p><p>Адрес: 197341, Санкт-Петербург, ул. Аккуратова, д. 2., тел.: +7 (812) 702-37-03</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильдарова</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ildarova</surname><given-names>Roza A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>Dmitry S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2209-7531</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova-Baranova</surname><given-names>Leyla S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2560-5167</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Покушалов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pokushalov</surname><given-names>Evgeniy A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>Sergey V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2466-7865</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Термосесов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Termosesov</surname><given-names>Sergey A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7115-0186</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Школьникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shkolnikova</surname><given-names>Maria A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр здоровья детей</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Children’s Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр имени В.А. Алмазова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский клинический институт педиатрии имени академика Ю.Е. Вельтищева Российского национального исследовательского медицинского университета имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education ‘Pirogov Russian National Research Medical University’ of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Meshalkin National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk National Research Medical Centre of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2019</year></pub-date><volume>15</volume><issue>6</issue><fpage>435</fpage><lpage>446</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баранов А.А., Васичкина Е.С., Ильдарова Р.А., Лебедев Д.С., Намазова-Баранова Л.С., Покушалов Е.А., Попов С.В., Термосесов С.А., Школьникова М.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Баранов А.А., Васичкина Е.С., Ильдарова Р.А., Лебедев Д.С., Намазова-Баранова Л.С., Покушалов Е.А., Попов С.В., Термосесов С.А., Школьникова М.А.</copyright-holder><copyright-holder xml:lang="en">Baranov A.A., Vasichkina E.S., Ildarova R.A., Lebedev D.S., Namazova-Baranova L.S., Pokushalov E.A., Popov S.V., Termosesov S.A., Shkolnikova M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/1678">https://www.pedpharma.ru/jour/article/view/1678</self-uri><abstract><p>В статье изложены обновленные данные о проблеме желудочковых экстрасистолий у детей, основанные на клинических рекомендациях Ассоциации детских кардиологов России и Союза педиатров России по диагностике, лечению и ведению пациентов детского возраста с желудочковой экстрасистолией. Подробно освещены вопросы диагностики, лечения, основанные на принципах доказательной медицины, а также важные аспекты профилактики обострений болезни и диспансерного наблюдения. Отображены критерии оценки качества медицинской помощи пациентам с желудочковыми экстрасистолиями.</p><p>Публикация является обновленным вариантом клинических рекомендаций Ассоциации детских кардиологов России и Союза педиатров России по диагностике, лечению и ведению пациентов детского возраста с желудочковой экстрасистолией, опубликованных на сайте <ext-link xlink:href="https://medi.ru/klinicheskie-rekomendatsii/zheludochkovaya-ekstrasistoliya-u-detej_14366/" ext-link-type="uri">https://medi.ru/klinicheskie-rekomendatsii/zheludochkovaya-ekstrasistoliya-u-detej_14366/</ext-link></p><p>Авторы подтверждают отсутствие конфликта интересов, который необходимо обнародовать.</p></abstract><trans-abstract xml:lang="en"><p>The article presents updated data on the problem of premature ventricular contractions in children based on the clinical guidelines of the Russian Society of Cardiology and the Union of Pediatricians of Russia for the diagnosis, treatment and management of pediatric patients with premature ventricular contraction. The issues of diagnosis and treatment based on the principles of evidence-based medicine as well as important aspects of prevention of exacerbations and follow-up have been clarified in detail. The criteria for assessing the quality of care for patients with premature ventricular contractions have been presented.</p><p>CONFLICT OF INTEREST. Not declared.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>желудочковые экстрасистолии</kwd><kwd>дети</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>профилактика</kwd><kwd>диспансерное наблюдение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>premature ventricular contractions</kwd><kwd>children</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd><kwd>prevention</kwd><kwd>follow-up</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Не указан.</funding-statement><funding-statement xml:lang="en">Not specified.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Beaufort-Krol GC, Dijkstra SS, Bink-Boelkens MT. Natural history of ventricular premature contractions in children with a structurally normal heart: does origin matter? Europace. 2008;10(8):998– 1003. doi: 10.1093/europace/eun121.</mixed-citation><mixed-citation xml:lang="en">Beaufort-Krol GC, Dijkstra SS, Bink-Boelkens MT. Natural history of ventricular premature contractions in children with a structurally normal heart: does origin matter? Europace. 2008;10(8):998– 1003. doi: 10.1093/europace/eun121.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Школьникова М.А., Березницкая В.В. Суправентрикулярные аритмии. Желудочковые аритмии. В кн.: Клинические рекомендации по детской кардиологии и ревматологии. / Под ред. М.А. Школьниковой, Е.И. Алексеевой. — М.: Ассоциация детских кардиологов России; 2011. — С. 133–159. [Shkol’nikova MA, Bereznitskaya VV. Supraventrikulyarnye aritmii. Zheludochkovye aritmii. In: Klinicheskie rekomendatsii po detskoi kardiologii i revmatologii. Ed by Shkol’nikova M.A., Alexeeva E.I. Moscow: Assotsiatsiya detskikh kardiologov Rossii; 2011. pp. 133–159. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Школьникова М.А., Березницкая В.В. Суправентрикулярные аритмии. Желудочковые аритмии. В кн.: Клинические рекомендации по детской кардиологии и ревматологии. / Под ред. М.А. Школьниковой, Е.И. Алексеевой. — М.: Ассоциация детских кардиологов России; 2011. — С. 133–159. [Shkol’nikova MA, Bereznitskaya VV. Supraventrikulyarnye aritmii. Zheludochkovye aritmii. In: Klinicheskie rekomendatsii po detskoi kardiologii i revmatologii. Ed by Shkol’nikova M.A., Alexeeva E.I. Moscow: Assotsiatsiya detskikh kardiologov Rossii; 2011. pp. 133–159. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Paul T, Marchal C, Garson A. Ventricular couplets in the young: prognosis related to underlying substrate. Am Heart J. 1990;119(3 Pt 1):577–582. doi: 10.1016/s0002-8703(05)80280-7.</mixed-citation><mixed-citation xml:lang="en">Paul T, Marchal C, Garson A. Ventricular couplets in the young: prognosis related to underlying substrate. Am Heart J. 1990;119(3 Pt 1):577–582. doi: 10.1016/s0002-8703(05)80280-7.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Dickinson DF, Scott O. Ambulatory electrocardiographic monitoring in 100 healthy teenage boys. Br Heart J. 1984;51(2):179– 183. doi: 10.1136/hrt.51.2.179.</mixed-citation><mixed-citation xml:lang="en">Dickinson DF, Scott O. Ambulatory electrocardiographic monitoring in 100 healthy teenage boys. Br Heart J. 1984;51(2):179– 183. doi: 10.1136/hrt.51.2.179.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Scott O, Williams GJ, Fiddler GI. Results of 24 hour ambulatory monitoring of electrocardiogram in 131 healthy boys aged 10 to 13 years. Br Heart J. 1980;44(3):304–308. doi: 10.1136/hrt.44.3.304.</mixed-citation><mixed-citation xml:lang="en">Scott O, Williams GJ, Fiddler GI. Results of 24 hour ambulatory monitoring of electrocardiogram in 131 healthy boys aged 10 to 13 years. Br Heart J. 1980;44(3):304–308. doi: 10.1136/hrt.44.3.304.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Southall DP, Richards J, Mitchell P, et al. Study of cardiac rhythm in healthy newborn infants. Br Heart J. 1980;43(1):14–20. doi: 10.1136/hrt.43.1.14.</mixed-citation><mixed-citation xml:lang="en">Southall DP, Richards J, Mitchell P, et al. Study of cardiac rhythm in healthy newborn infants. Br Heart J. 1980;43(1):14–20. doi: 10.1136/hrt.43.1.14.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Nagashima M, Matsushima M, Ogawa A, et al. Cardiac arrhythmias in healthy children revealed by 24-hour ambulatory ECG monitoring. Pediatr Cardiol. 1987;8(2):103–108. doi: 10.1007/ BF02079464.</mixed-citation><mixed-citation xml:lang="en">Nagashima M, Matsushima M, Ogawa A, et al. Cardiac arrhythmias in healthy children revealed by 24-hour ambulatory ECG monitoring. Pediatr Cardiol. 1987;8(2):103–108. doi: 10.1007/ BF02079464.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Marcus FI, McKenna WJ, Sherrill D, et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria. Eur Heart J. 2010;31(7):806–814. doi: 10.1093/eurheartj/ehq025.</mixed-citation><mixed-citation xml:lang="en">Marcus FI, McKenna WJ, Sherrill D, et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria. Eur Heart J. 2010;31(7):806–814. doi: 10.1093/eurheartj/ehq025.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Crosson JE, Callans DJ, Bradley DJ, et al. PACES/HRS expert consensus statement on the evaluation and management of ventricular arrhythmias in the child with a structurally normal heart. Heart Rhythm. 2014;11(9):e55–78. doi: 10.1016/j.hrthm.2014.05.010.</mixed-citation><mixed-citation xml:lang="en">Crosson JE, Callans DJ, Bradley DJ, et al. PACES/HRS expert consensus statement on the evaluation and management of ventricular arrhythmias in the child with a structurally normal heart. Heart Rhythm. 2014;11(9):e55–78. doi: 10.1016/j.hrthm.2014.05.010.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bigger JT. Identification of patients at high risk for sudden cardiac death. Am J Cardiol. 1984;54(9):3D–8D. doi: 10.1016/ s0002-9149(84)80277-5.</mixed-citation><mixed-citation xml:lang="en">Bigger JT. Identification of patients at high risk for sudden cardiac death. Am J Cardiol. 1984;54(9):3D–8D. doi: 10.1016/ s0002-9149(84)80277-5.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Ackerman MJ, Priori SG, Willems S, et al. HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA). Europace. 2011;13(8):1077–1109. doi: 10.1093/europace/eur245.</mixed-citation><mixed-citation xml:lang="en">Ackerman MJ, Priori SG, Willems S, et al. HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA). Europace. 2011;13(8):1077–1109. doi: 10.1093/europace/eur245.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Priori SG, Wilde AA, Horie M, et al. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013. Heart Rhythm. 2013;10(12):1932–1963. doi: 10.1016/j.hrthm.2013.05.014.</mixed-citation><mixed-citation xml:lang="en">Priori SG, Wilde AA, Horie M, et al. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013. Heart Rhythm. 2013;10(12):1932–1963. doi: 10.1016/j.hrthm.2013.05.014.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации по проведению электрофизиологических исследований, катетерной абляции и применению имплантируемых антиаритмических устройств. 3-е изд., доп. и перераб. — М.: МАКС-Пресс; 2013. — 596 с. [Klinicheskie rekomendatsii po provedeniyu elektrofiziologicheskikh issledovanii, kateternoi ablyatsii i primeneniyu implantiruemykh antiaritmicheskikh ustroistv. 3th ed., revised and updated. Moscow: MAKS-Press; 2013. 596 p. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Клинические рекомендации по проведению электрофизиологических исследований, катетерной абляции и применению имплантируемых антиаритмических устройств. 3-е изд., доп. и перераб. — М.: МАКС-Пресс; 2013. — 596 с. [Klinicheskie rekomendatsii po provedeniyu elektrofiziologicheskikh issledovanii, kateternoi ablyatsii i primeneniyu implantiruemykh antiaritmicheskikh ustroistv. 3th ed., revised and updated. Moscow: MAKS-Press; 2013. 596 p. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Radford D. Side effects of verapamil in infants. Arch Dis Child. 1983;58(6):465–466. doi: 10.1136/adc.58.6.465.</mixed-citation><mixed-citation xml:lang="en">Radford D. Side effects of verapamil in infants. Arch Dis Child. 1983;58(6):465–466. doi: 10.1136/adc.58.6.465.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Wetzel GT, Klitzner TS. Developmental cardiac electrophysiology recent advances in cellular physiology. Cardiovasc Res. 1996;31 Spec No:52–60. doi: 10.1016/0008-6363(95)00158-1.</mixed-citation><mixed-citation xml:lang="en">Wetzel GT, Klitzner TS. Developmental cardiac electrophysiology recent advances in cellular physiology. Cardiovasc Res. 1996;31 Spec No:52–60. doi: 10.1016/0008-6363(95)00158-1.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lapage MJ, Bradley DJ, Dick M. Verapamil in infants: an exaggerated fear? Pediatr Cardiol. 2013;34(7):1532–1534. doi: 10.1007/s00246-013-0739-8.</mixed-citation><mixed-citation xml:lang="en">Lapage MJ, Bradley DJ, Dick M. Verapamil in infants: an exaggerated fear? Pediatr Cardiol. 2013;34(7):1532–1534. doi: 10.1007/s00246-013-0739-8.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
