ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v10i6.904ppharm-165Research ArticleКЛИНИЧЕСКИЙ СЛУЧАЙCASE REPORTОПЫТ ПРИМЕНЕНИЯ АДАЛИМУМАБА У ПАЦИЕНТА С ЮВЕНИЛЬНЫМ ОЛИГОАРТРИТОМ И УВЕИТОМADALIMUMAB USAGE CASE IN A PATIENT WITH JUVENILE OLIGOARTHRITIS AND UVEITISБалыковаЛ. А.BalykovaL. A.

доктор медицинских наук, профессор, заведующая кафедрой педиатрии Мордовского государственногоуниверситета им. Н.П. Огарёва

PhD, Professor, head of the pediatrics department at the Ogaryov Mordovia State University

larisabalykova@yandex.ruИвянскаяН. В.IvyanskayaN. V.АрзамаскинаТ. Н.ArzamaskinaT. N.МакаркинаЕ. В.MakarkinaE. V.ЛавскаяЯ. В.LavskayaYa. V.Мордовский государственный университет им. Н.П. Огарёва, СаранскРоссияOgaryov Mordovia State University, SaranskRussian FederationМордовская детская республиканская клиническая больница № 2, Саранск, Российская ФедерацияРоссияRepublican Child Hospital № 2, Saransk, Mordovia, RussiaRussian FederationМордовский государственный университет им. Н.П. Огарёва, Саранск, Российская ФедерацияРоссияOgarev Mordovian State Medical University, Saransk, RussiaRussian Federation201302122013106Педиатрическая фармакология9397Copyright © Балыкова Л.А., Ивянская Н.В., Арзамаскина Т.Н., Макаркина Е.В., Лавская Я.В., 20132013Балыкова Л.А., Ивянская Н.В., Арзамаскина Т.Н., Макаркина Е.В., Лавская Я.В.Balykova L.A., Ivyanskaya N.V., Arzamaskina T.N., Makarkina E.V., Lavskaya Y.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/165

The article presents a case of a severe progressive course of a juvenile arthritis refractory to the standard antirheumatic therapy. Due to oligosymptomatic disease onset and low adherence of the patient to treatment, the disease was characterized by development of polyarticular joint syndrome with destructive changes (aseptic whirlbone necrosis) and formation of uveitis complicated by a cataract and patient’s incapacitation. Prescription of adalimumab allowed reducing activity of the inflammatory process, considerably improving function of the affected joints, terminating pain syndrome and stiffness and inducing remission of uveitis.

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The authors declare that there are no conflicts of interest present.