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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v14i6.1834</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-1580</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПРАКТИКУ ПЕДИАТРА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>For Pediatricians' Practice</subject></subj-group></article-categories><title-group><article-title>Нерациональное использование антибиотиков в медицине: кризис антибиотикорезистентности, и что мы можем сделать</article-title><trans-title-group xml:lang="en"><trans-title>Irrational Use of Antibiotics in Medicine: Crisis of Antibiotic Resistance and what We Can Do</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7222-6760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyina</surname><given-names>Svetlana V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующая кафедрой детских инфекционных болезней Иркутского государственного медицинского университета</p><p>Адрес: 664043, Иркутск, ул. Маршала Конева, д. 90, к. 4, тел.: +7 (3952) 30-04-46</p></bio><email xlink:type="simple">dr_ilina@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State-Funded Educational Institution of Higher Education «Irkutsk State Medical University» of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>29</day><month>01</month><year>2018</year></pub-date><volume>14</volume><issue>6</issue><fpage>508</fpage><lpage>514</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ильина С.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Ильина С.В.</copyright-holder><copyright-holder xml:lang="en">Ilyina S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/1580">https://www.pedpharma.ru/jour/article/view/1580</self-uri><abstract><p>Избыточное использование антибиотиков в клинической практике не только увеличивает стоимость лечения и создает риск нежелательных побочных эффектов, но и ведет к росту  резистентности микроорганизмов. Эта проблема является глобальной и от ее решения зависит,  сможет ли человечество в дальнейшем эффективно бороться с бактериальной инфекцией. В  статье представлен краткий обзор основных ситуаций нерационального назначения  антибиотиков в педиатрии и причин, по которым врачи назначают антибиотики, когда они не  нужны. На основании анализа источников литературы предложены некоторые стратегии  борьбы с избыточным назначением антибиотиков и сформулированы обобщенные правила  рациональной антибиотикотерапии для врачей и пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Antibiotic overuse in clinical practice not only leads to an increased amount of healthcare costs and a risk of side effects, but also causes an increase of antimicrobial resistance. This is a global problem and an  effective fight bacterial infection depends on its solution. This article  provides a brief overview of the primary situations of irrational antibiotic use among pediatric population and the reasons why doctors  overprescribe antibiotic. The literature based strategies for antibiotics  restrictions are proposed and some generalized rules for a rational antibiotic therapy for physicians and for patients are formulated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антибиотикорезистентность</kwd><kwd>рациональное использование антибиотиков</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antibioticresistance</kwd><kwd>rational use of antibiotics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Таточенко В.К., Бакрадзе М.Д. Лихорадка неясной этиологии у детей // Инфекционные болезни. — 2008. — Т.6. — №2 — C. 76–81. [Tatochenko VK, Bakradze MD. Fever of unknown etiology in children. Infectious diseases. 2008;6(2):76–81. 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