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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v14i5.1788</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-1563</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Функциональные расстройства органов пищеварения у детей: отдаленные последствия  и современные возможности предупреждения и коррекции</article-title><trans-title-group xml:lang="en"><trans-title>Functional Gastrointestinal Disorders in Infants: Long-Tern Consequences and Modern Approaches for Prevention and Treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1082-8632</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>Evgeniya G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>гиевна, кандидат медицинских наук, медицинский научный советник</p></bio><email xlink:type="simple">evgeniya.makarova@ru.nestle.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6540-9630</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Украинцев</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ukraintsev</surname><given-names>Sergei E.</given-names></name></name-alternatives><email xlink:type="simple">evgeniya.makarova@ru.nestle.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «Нестле Россия», Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Nestle Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Нестле Россия», Москва;&#13;
Национальный медицинский исследовательский центр здоровья детей, Москва, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Nestle Russia, Moscow;&#13;
Nationa l Medical Research Center of Children,s Health, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>13</day><month>12</month><year>2017</year></pub-date><volume>14</volume><issue>5</issue><fpage>392</fpage><lpage>399</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макарова Е.Г., Украинцев С.Е., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Макарова Е.Г., Украинцев С.Е.</copyright-holder><copyright-holder xml:lang="en">Makarova E.G., Ukraintsev S.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/1563">https://www.pedpharma.ru/jour/article/view/1563</self-uri><abstract><p>В статье обсуждаются современные представления о генезе наиболее распространенных вариантов функциональных расстройств органов пищеварения у детей, в том числе их долгосрочные негативные последствия для здоровья ребенка. Представлены данные о роли кишечной микробиоты в формировании функциональных расстройств органов пищеварения, а также современные подходы к их предупреждению и коррекции с помощью пробиотиков с доказанной эффективностью.</p></abstract><trans-abstract xml:lang="en"><p>The article discusses modern ideas about the genesis of the most common variants of functional gastrointestinal disorders (FGID) in infants, and their ability to lead to long-term negative consequences for the health of the child. The article provides data on role of intestinal microbiota in development of FGID in infants and current approaches to prevention and correction using probiotics with proven effectiveness.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональные расстройства органов пищеварения</kwd><kwd>младенцы</kwd><kwd>колики</kwd><kwd>пробиотики</kwd><kwd>Lactobacillus reuteri</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional gastrointestinal disorders</kwd><kwd>infants</kwd><kwd>colic</kwd><kwd>probiotics</kwd><kwd>Lactobacillus reuteri</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при поддержке ООО «Нестле Россия»</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Drossman DA, Dumitrascu DL. Rome III: New standard for functional gastrointestinal disorders. 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