ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v10i6.895ppharm-156Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWАЛЛЕРГИЯ НА АНТИБИОТИКИ У ДЕТЕЙ: КТО ВИНОВАТ И ЧТО ДЕЛАТЬ?ALLERGY TO ANTIBIOTICS IN CHILDREN: WHO IS TO BLAME AND WHAT TO DO?АндрееваИ. В.AndreevaI. V.

кандидат медицинских наук, доцент, старший научный сотрудник НИИ антимикробной химиотерапии ГБОУ ВПО «Смоленская государственная медицинская академия» Министерства здравоохранения России

MD, associate professor, senior research scientist at the research institute of antimicrobial chemotherapy SBEI HPE “Smolensk State Medical Academy” of the Ministry of Health of Russia

Irina.Andreeva@antibiotic.ruСтецюкО. У.StetsyukO. U.НИИ антимикробной химиотерапии ГБОУ ВПО «Смоленская государственная медицинская академия» Минздрава РоссииРоссияResearch institute of antimicrobial chemotherapy SBEI HPE “Smolensk State Medical Academy” of the Ministry of Health of RussiaRussian Federation201302122013106Педиатрическая фармакология4252Copyright © Андреева И.В., Стецюк О.У., 20132013Андреева И.В., Стецюк О.У.Andreeva I.V., Stetsyuk O.U.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/156

Allergic reactions to antibiotics are a serious issue of pediatric practice and a difficult problem for pediatricians due to difficulties of diagnostics, interpretation of anamnestic data and subsequent selection of adequate antibacterial therapy. The review describes the main types of allergic reactions to the antibacterial drugs most widely used in children. Special attention is given to drug hypersensitivity development risk factors; clinical manifestations of allergy to antibiotics and peculiarities of allergic reactions to certain drugs are described. The article dwells upon clinical approaches and algorithms of managing patients with presumed intolerance to antibacterial drugs.

ведения пациентов с предполагаемой непереносимостью антибактериальных препаратов. антибиотикиантибактериальные препаратыаллергические реакциилекарственная гиперчувствительностьаллергиянепереносимостьфакторы рискаantibioticsantibacterial drugsallergic reactionsdrug hypersensitivityallergyintolerancerisk factorsReferencesIbia E. O., Schwartz R. H., Wiedermann B. L. Antibiotic rashes in children: a survey in a private practice setting. Arch. Dermatol. 2000; 136 (7): 849–854.Ibia E. O., Schwartz R. H., Wiedermann B. L. Antibiotic rashes in children: a survey in a private practice setting. Arch. Dermatol. 2000; 136 (7): 849–854.Menniti-Ippolito G., Raschetti R., Da Cas R. et al. Active monitoring of adverse drug reactions in children. Italian Paediatric Pharmaco surveillance Multicenter Group. Lancet. 2000; 355: 1613–1614.Menniti-Ippolito G., Raschetti R., Da Cas R. et al. Active monitoring of adverse drug reactions in children. Italian Paediatric Pharmaco surveillance Multicenter Group. 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The authors declare that there are no conflicts of interest present.