ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v13i5.1640ppharm-1463Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWОсобенности физического и нервно- психического развития детей с низкой, очень низкой и экстремально низкой массой тела при рождении в различные возрастные периоды жизниFeatures of Physical and Neuro-Psychological Development of Children with Low, Very Low and Extremely Low Birth Weight in Different Age Periods of Lifehttps://orcid.org/0000-0002-4449-4810ДеевИ. А.DeevI. A.

Томск, Российская Федерация

Tomsk, Russian Federation

https://orcid.org/0000-0001-8926-5918КуликоваК. В.KulikovaK. V.

ассистент кафедры факультетской педиатрии с курсом детских болезней лечебного факультета СибГМУ Адрес: 634050, Томск, Московский тракт, д. 2

Tomsk, Russian Federation

kristina.v.kulikova@gmail.comhttps://orcid.org/0000-0003-0098-1403КобяковаО. С.KobyakovaO. S.

Томск, Российская Федерация

Tomsk, Russian Federation

https://orcid.org/0000-0002-0088-9204КуликовЕ. С.KulikovE. S.

Томск, Российская Федерация

Tomsk, Russian Federation

https://orcid.org/0000-0002-0352-2563ДееваЕ. В.DeevaE. V.

Томск, Российская Федерация

Tomsk, Russian Federation

https://orcid.org/0000-0001-5828-231XКоломеецИ. Л.KolomeetsI. L.

Томск, Российская Федерация

Tomsk, Russian Federation

Сибирский государственный медицинский университетРоссияSiberian State Medical UniversityRussian Federation201616122016135448451Copyright © Деев И.А., Куликова К.В., Кобякова О.С., Куликов Е.С., Деева Е.В., Коломеец И.Л., 20162016Деев И.А., Куликова К.В., Кобякова О.С., Куликов Е.С., Деева Е.В., Коломеец И.Л.Deev I.A., Kulikova K.V., Kobyakova O.S., Kulikov E.S., Deeva E.V., Kolomeets I.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/1463

Анализ особенностей физического и нервно-психического развития детей с низкой, очень низкой и экстремально низкой массой тела при рождении в различные возрастные периоды жизни выполнен по данным когортных исследований новорожденных с различным сроком гестации и массой тела, представленных в электронных базах PubMed и Medscape. Обнаружено, что у подавляющего числа детей с низкой, очень низкой и экстремально низкой массой тела при рождении к старшему возрасту развиваются нарушения физического и нервно-психического развития, слуха и зрения различной степени выраженности, двигательной функции, интеллекта и когнитивных навыков. В этой связи актуальным остается не только разработка новых технологий реанимации и интенсивной терапии новорожденных, но и обеспечение адекватной профилактики преждевременных родов в группе женщин с высокой степенью перинатального риска. Все это позволит в будущем предотвратить рост среди недоношенных числа детей с инвалидизирующими состояниями.

Analysis of features of physical and neuro-psychological development of children with low, very low and extremely low birth weight in different age periods is carried out according to cohort studies of newborns with different gestational age and birth weight, presented in electronic databases PubMed and Medscape. It is revealed that the overwhelming number of children with low, very low and extremely low birth weight, gain physical and neuro- psychological development impairments, hearing and vision disorders of varying severity, violation of motor function, intelligence and cognitive skills infringement in an older age. In this regard, it is actual not only to develop new neonatal reanimation and intensive care technologies, but also to ensure adequate prevention of preterm birth in the group of women with a high degree of perinatal risk. All this will further allow preventing increase in children with disabling conditions number among premature infants.

недоношенные детифизическое развитиедетский церебральный параличнервно-психическое развитиеинвалидностьpremature infantsphysical developmentinfantile cerebral palsyneuro-psychological developmentdisabilitiesReferencesSoll RF. Progress in the care of extremely preterm infant. JAMA. 2015;314(10):1007–1008. doi: 10.1001/jama.2015.10911.Soll RF. Progress in the care of extremely preterm infant. JAMA. 2015;314(10):1007–1008. doi: 10.1001/jama.2015.10911.Bocca-Tjeertes IF, Kerstjens JM, Reijneveld SA, et al. Growth and predictors of growth restraint in moderately preterm children aged 0 to 4 years. Pediatrics. 2011;128(5):e1187– 1194. doi: 10.1542/peds.2010-3781.Bocca-Tjeertes IF, Kerstjens JM, Reijneveld SA, et al. Growth and predictors of growth restraint in moderately preterm children aged 0 to 4 years. Pediatrics. 2011;128(5):e1187– 1194. doi: 10.1542/peds.2010-3781.Pierrat V, Marchand-Martin L, Guemas I, et al. Height at 2 and 5 years of age in children born very preterm: the EPIPAGE study. Arch Dis Child Fetal Neonatal Ed. 2011;96(5):F348– 354. doi: 10.1136/adc.2010.185470.Pierrat V, Marchand-Martin L, Guemas I, et al. Height at 2 and 5 years of age in children born very preterm: the EPIPAGE study. Arch Dis Child Fetal Neonatal Ed. 2011;96(5):F348– 354. doi: 10.1136/adc.2010.185470.Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008;359(1):61–73. doi: 10.1056/NEJMra0708473.Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008;359(1):61–73. doi: 10.1056/NEJMra0708473.Casey PH, Bradley RH, Whiteside-Mansell L, et al. Evolution of obesity in a low birth weight cohort. J Perinatol. 2012;32(2):91–96. doi: 10.1038/jp.2011.75.Casey PH, Bradley RH, Whiteside-Mansell L, et al. Evolution of obesity in a low birth weight cohort. J Perinatol. 2012;32(2):91–96. doi: 10.1038/jp.2011.75.van Haastert IC, de Vries LS, Helders PJ, Jongmans MJ. Early gross motor development of preterm infants according to the Alberta Infant Motor Scale. J Pediatr. 2006;149(5):617– 622. doi: 10.1016/j.jpeds.2006.07.025.van Haastert IC, de Vries LS, Helders PJ, Jongmans MJ. Early gross motor development of preterm infants according to the Alberta Infant Motor Scale. J Pediatr. 2006;149(5):617– 622. doi: 10.1016/j.jpeds.2006.07.025.Pin TW, Darrer T, Eldridge B, Galea MP. Motor development from 4 to 8 months corrected age in infants born at or less than 29 weeks gestation. Dev Med Child Neurol. 2009;51(9):739–745. doi: 10.1111/j.1469-8749.2009.03265.x.Pin TW, Darrer T, Eldridge B, Galea MP. Motor development from 4 to 8 months corrected age in infants born at or less than 29 weeks gestation. Dev Med Child Neurol. 2009;51(9):739–745. doi: 10.1111/j.1469-8749.2009.03265.x.Pin TW, Eldridge B, Galea MP. Motor trajectories from 4 to 18 months corrected age in infants born at less than 30 weeks of gestation. Early Hum Dev. 2010;86(9):573–580. doi: 10.1016/j.earlhumdev.2010.07.008.Pin TW, Eldridge B, Galea MP. Motor trajectories from 4 to 18 months corrected age in infants born at less than 30 weeks of gestation. Early Hum Dev. 2010;86(9):573–580. doi: 10.1016/j.earlhumdev.2010.07.008.Ferrari F, Gallo C, Pugliese M, et al. Preterm birth and developmental problems in the preschool age. Part I: minor motor problems. J Matern Fetal Neonatal Med. 2012;25(11):2154–2159. doi: 10.3109/14767058.2012.696164.Ferrari F, Gallo C, Pugliese M, et al. Preterm birth and developmental problems in the preschool age. Part I: minor motor problems. J Matern Fetal Neonatal Med. 2012;25(11):2154–2159. doi: 10.3109/14767058.2012.696164.Husby IM, Skranes J, Olsen A, et al. Motor skills at 23 years of age in young adults born preterm with very low birth weight. Early Hum Dev. 2013;89(9):747–754. doi: 10.1016/j.earlhumdev.2013.05.009.Husby IM, Skranes J, Olsen A, et al. Motor skills at 23 years of age in young adults born preterm with very low birth weight. Early Hum Dev. 2013;89(9):747–754. doi: 10.1016/j.earlhumdev.2013.05.009.Bos AF, van Braeckel KN, Hitzert MM, et al. Development of fine motor skills in preterm infants. Dev Med Child Neurol. 2013;55 Suppl 4:1–4. doi: 10.1111/dmcn.12297.Bos AF, van Braeckel KN, Hitzert MM, et al. Development of fine motor skills in preterm infants. Dev Med Child Neurol. 2013;55 Suppl 4:1–4. doi: 10.1111/dmcn.12297.Edwards J, Berube M, Erlandson K, et al. Developmental coordination disorder in school- aged children born very preterm and/ or at very low birth weight: a systematic review. J Dev Behav Pediatr. 2011;32(9):678–687. doi: 10.1097/DBP.0b013e31822a396a.Edwards J, Berube M, Erlandson K, et al. Developmental coordination disorder in school- aged children born very preterm and/ or at very low birth weight: a systematic review. J Dev Behav Pediatr. 2011;32(9):678–687. doi: 10.1097/DBP.0b013e31822a396a.Faebo Larsen R, Hvas Mortensen L, Martinussen T, Nybo Andersen AM. Determinants of developmental coordination disorder in 7-year-old children: a study of children in the Danish National Birth Cohort. Dev Med Child Neurol. 2013;55(11):1016–1022. doi: 10.1111/dmcn.12223.Faebo Larsen R, Hvas Mortensen L, Martinussen T, Nybo Andersen AM. Determinants of developmental coordination disorder in 7-year-old children: a study of children in the Danish National Birth Cohort. Dev Med Child Neurol. 2013;55(11):1016–1022. doi: 10.1111/dmcn.12223.Himpens E, van den Broeck C, Oostra A, et al. Prevalence, type, distribution, and severity of cerebral palsy in relation to gestational age: a meta-analytic review. Dev Med Child Neurol. 2008;50(5):334–340. doi: 10.1111/j.1469-8749.2008.02047.x.Himpens E, van den Broeck C, Oostra A, et al. Prevalence, type, distribution, and severity of cerebral palsy in relation to gestational age: a meta-analytic review. Dev Med Child Neurol. 2008;50(5):334–340. doi: 10.1111/j.1469-8749.2008.02047.x.Blencowe H, Lee AC, Cousens S, et al. Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010. Pediatr Res. 2013;74 Suppl 1:17–34. doi: 10.1038/pr.2013.204.Blencowe H, Lee AC, Cousens S, et al. Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010. Pediatr Res. 2013;74 Suppl 1:17–34. doi: 10.1038/pr.2013.204.Vieira ME, Linhares MB. Developmental outcomes and quality of life in children born preterm at preschool- and school-age. J Pediatr (Rio J). 2011;87(4):281–291. doi: 10.2223/JPED.2096.Vieira ME, Linhares MB. Developmental outcomes and quality of life in children born preterm at preschool- and school-age. J Pediatr (Rio J). 2011;87(4):281–291. doi: 10.2223/JPED.2096.Pesonen AK, Raikkonen K, Heinonen K, et al. Personality of young adults born prematurely: the Helsinki study of very low birth weight adults. J Child Psychol Psychiatry. 2008;49(6):609–617. doi: 10.1111/j.1469-7610.2007.01874.x.Pesonen AK, Raikkonen K, Heinonen K, et al. Personality of young adults born prematurely: the Helsinki study of very low birth weight adults. J Child Psychol Psychiatry. 2008;49(6):609–617. doi: 10.1111/j.1469-7610.2007.01874.x.Jones KM, Champion PR, Woodward LJ. Social competence of preschool children born very preterm. Early Hum Dev. 2013; 89(10):795–802. doi: 10.1016/j.earlhumdev.2013.06.008.Jones KM, Champion PR, Woodward LJ. Social competence of preschool children born very preterm. Early Hum Dev. 2013; 89(10):795–802. doi: 10.1016/j.earlhumdev.2013.06.008.Ribeiro LA, Zachrisson HD, Schjolberg S, et al. Attention problems and language development in preterm low-birth-weight children: cross-lagged relations from 18 to 36 months. BMC Pediatr. 2011;11:59. doi: 10.1186/1471-2431-11-59.Ribeiro LA, Zachrisson HD, Schjolberg S, et al. Attention problems and language development in preterm low-birth-weight children: cross-lagged relations from 18 to 36 months. BMC Pediatr. 2011;11:59. doi: 10.1186/1471-2431-11-59.Ko G, Shah P, Lee SK, Asztalos E. Impact of maternal education on cognitive and language scores at 18 to 24 months among extremely preterm neonates. Am J Perinatol. 2013;30(9):723–730. doi: 10.1055/s-0032-1331034.Ko G, Shah P, Lee SK, Asztalos E. Impact of maternal education on cognitive and language scores at 18 to 24 months among extremely preterm neonates. Am J Perinatol. 2013;30(9):723–730. doi: 10.1055/s-0032-1331034.Lee ES, Yeatman JD, Luna B, Feldman HM. Specific language and reading skills in school- aged children and adolescents are associated with prematurity after controlling for IQ. Neuro psychologia. 2011;49(5):906–913. doi: 10.1016/j.neuropsychologia.2010.12.038.Lee ES, Yeatman JD, Luna B, Feldman HM. Specific language and reading skills in school- aged children and adolescents are associated with prematurity after controlling for IQ. Neuro psychologia. 2011;49(5):906–913. doi: 10.1016/j.neuropsychologia.2010.12.038.Hutchinson EA, De Luca CR, Doyle LW, et al. School-age outcomes of extremely preterm or extremely low birth weight children. Pediatrics. 2013;131(4):e1053–1061. doi: 10.1542/peds.2012-2311.Hutchinson EA, De Luca CR, Doyle LW, et al. School-age outcomes of extremely preterm or extremely low birth weight children. Pediatrics. 2013;131(4):e1053–1061. doi: 10.1542/peds.2012-2311.Guellec I, Lapillonne A, Renolleau S, et al. Neurologic outcomes at school age in very preterm infants born with severe or mild growth restriction. Pediatrics. 2011;127(4):e883– 991. doi: 10.1542/peds.2010-2442.Guellec I, Lapillonne A, Renolleau S, et al. Neurologic outcomes at school age in very preterm infants born with severe or mild growth restriction. Pediatrics. 2011;127(4):e883– 991. doi: 10.1542/peds.2010-2442.Blencowe H, Lawn JE, Vazquez T, et al. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res. 2013;74 Suppl 1:35–49. doi: 10.1038/pr.2013.205.Blencowe H, Lawn JE, Vazquez T, et al. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res. 2013;74 Suppl 1:35–49. doi: 10.1038/pr.2013.205.Phadke A, Msall ME, Droste P, et al. Impaired visual fixation at the age of 2 years in children born before the twenty-eighth week of gestation. Antecedents and correlates in the multicenter ELGAN study. Pediatr Neurol. 2014;51(1):36–42. doi: 10.1016/j.pediatrneurol.2014.03.007.Phadke A, Msall ME, Droste P, et al. Impaired visual fixation at the age of 2 years in children born before the twenty-eighth week of gestation. Antecedents and correlates in the multicenter ELGAN study. Pediatr Neurol. 2014;51(1):36–42. doi: 10.1016/j.pediatrneurol.2014.03.007.Synnes AR, Anson S, Baum J, Usher L. Incidence and pattern of hearing impairment in children with 800 g birth weight in British Columbia, Canada. Acta Paediatr. 2012;101(2):e48–54. doi: 10.1111/j.1651-2227.2011.02437.x.Synnes AR, Anson S, Baum J, Usher L. Incidence and pattern of hearing impairment in children with 800 g birth weight in British Columbia, Canada. Acta Paediatr. 2012;101(2):e48–54. doi: 10.1111/j.1651-2227.2011.02437.x.

The authors declare that there are no conflicts of interest present.