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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v11i1.900</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-144</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИАГНОСТИКА В ПЕДИАТРИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PEDIATRIC DIAGNOSTICS</subject></subj-group></article-categories><title-group><article-title>ИСПОЛЬЗОВАНИЕ ДИФФУЗИОННО- ВЗВЕШЕННОЙ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ ДЛЯ ВЫЯВЛЕНИЯ ГИПОКСИЧЕСКИ-ИШЕМИЧЕСКИХ ПОРАЖЕНИЙ ГОЛОВНОГО МОЗГА У НОВОРОЖДЕННЫХ</article-title><trans-title-group xml:lang="en"><trans-title>USE OF DIFFUSION-WEIGHTED MAGNETIC RESONANCE IMAGING FOR REVEALING HYPOXIC-ISCHEMIC BRAIN LESIONS IN NEONATES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шимченко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shimchenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-невролог, заочный аспирант кафедры педиатрии с курсом неонатологии Кубанского государственногомедицинского университета, заведующая педиатрическим отделением Краснодарской городской клинической больницы скорой медицинской помощи</p></bio><bio xml:lang="en"><p>neurologist, extramural postgraduate of the department of pediatrics with a course of neonatology at Kuban State Medical University, head of the pediatric department at Krasnodar city clinical emergency hospital</p></bio><email xlink:type="simple">ev2273@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клещенко</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kleshchenko</surname><given-names>E. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голосеев</surname><given-names>К. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Goloseyev</surname><given-names>K. F.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кубанский государственный медицинский университет, Краснодар&#13;
Краснодарская городская клиническая больница скорой медицинской помощи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University, Moscow&#13;
Krasnodar City Clinical Emergency Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кубанский государственный медицинский университет, Краснодар, Российская Федерация&#13;
Детская краевая клиническая больница, Краснодар, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University, Krasnodar, Russian Federation&#13;
Children’s territorial clinical hospital, Krasnodar, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Детская краевая клиническая больница, Краснодар, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Children’s territorial clinical hospital, Krasnodar, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>15</day><month>02</month><year>2014</year></pub-date><volume>11</volume><issue>1</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>69</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шимченко Е.В., Клещенко Е.И., Голосеев К.Ф., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Шимченко Е.В., Клещенко Е.И., Голосеев К.Ф.</copyright-holder><copyright-holder xml:lang="en">Shimchenko E.V., Kleshchenko E.I., Goloseyev K.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/144">https://www.pedpharma.ru/jour/article/view/144</self-uri><abstract/><trans-abstract xml:lang="en"><p>The article presents advantages of use of diffusion-weighted magnetic resonance imaging (DW MRI) for revealing hypoxic-ischemic brain lesions in neonates. The trial included 97 neonates with perinatal brain lesion who had been undergoing treatment at a resuscitation department or neonatal pathology department in the first month of life. The article shows high information value of diffusion-weighted images (DWI) for diagnostics of hypoxic-ischemic lesions in comparison with regular standard modes. In the event of no structural brain lesions of neonates, pronounced increase in signal characteristics revealed by DWI indicated considerable pathophysiological alterations. Subsequently, children developed structural alterations in the form of cystic encephalomalacia with expansion of cerebrospinal fluid spaces manifested with pronounced neurological deficit. DW MRI has been offered as a method of prognosticating further neurological development of children on early stages.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>новорожденный</kwd><kwd>магнитно-резонансная томография</kwd><kwd>диффузионно-взвешенное изображение</kwd><kwd>гипоксически-ишемическое поражение</kwd><kwd>головной мозг</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neonate</kwd><kwd>magnetic resonance imaging</kwd><kwd>diffusion-weighted image</kwd><kwd>hypoxic-ischemic lesion</kwd><kwd>brain</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Барашнев Ю. И. Перинатальная неврология. Москва: Издательство Триада-Х. 2001. 638 с.</mixed-citation><mixed-citation xml:lang="en">Barashnev Yu.I. Perinatal'naya nevrologiya [Perinatal Neurology]. 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