<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ppharm-1238</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕДАКЦИОННЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>AN EDITORIAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>ТЯЖЕЛЫЕ ХРОНИЧЕСКИЕ АЛЛЕРГИЧЕСКИЕ И АССОЦИИРОВАННЫЕ С НИМИ БОЛЕЗНИ: ЕДИНЫЙ ПОДХОД — МЕМОРАНДУМ MEDALL-GA2LEN-ARIA СОВМЕСТНО С ЦЕНТРОМ ВОЗ ПО БОРЬБЕ С АСТМОЙ И РИНИТОМ 2001-05-22 D3 (АНГЛИЙСКИЙ и РУССКИЙ ВАРИАНТ)</article-title><trans-title-group xml:lang="en"><trans-title>SEVERE CHRONIC ALLERGIC (AND RELATED) DISEASES: A UNIFORM APPROACH — A MEDALL-GA2LEN-ARIA POSITION PAPER IN COLLABORATION WITH THE WHO COLLABORATING CENTER FOR ASTHMA AND RHINITIS (ENGLISH &amp; RUSSIAN VARIANTS)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Bousquet</surname><given-names>J.</given-names></name><name name-style="western" xml:lang="en"><surname>Bousquet</surname><given-names>J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of MeDALL (Mechanisms of the Development of ALLergy, Grant Agreement FP7 N°264357, MeDALL paper N°5)Member of ARIA (Allergic Rhinitis and its Impact on Asthma)WHO Collaborating Center for Asthma and Rhinitis (Montpellier)Espace Francophone de Pneumologie (Societe de Pneumologie de Langue Francaise)</p></bio><bio xml:lang="en"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of MeDALL (Mechanisms of the Development of ALLergy, Grant Agreement FP7 N°264357, MeDALL paper N°5)Member of ARIA (Allergic Rhinitis and its Impact on Asthma)WHO Collaborating Center for Asthma and Rhinitis (Montpellier)Espace Francophone de Pneumologie (Societe de Pneumologie de Langue Francaise)</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Anto</surname><given-names>J.M.</given-names></name><name name-style="western" xml:lang="en"><surname>Anto</surname><given-names>J.M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of MeDALL (Mechanisms of the Development of ALLergy, Grant Agreement FP7 N°264357, MeDALL paper N°5)</p></bio><bio xml:lang="en"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of MeDALL (Mechanisms of the Development of ALLergy, Grant Agreement FP7 N°264357, MeDALL paper N°5)</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Demoly</surname><given-names>P.</given-names></name><name name-style="western" xml:lang="en"><surname>Demoly</surname><given-names>P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of ARIA (Allergic Rhinitis and its Impact on Asthma)WHO Collaborating Center for Asthma and Rhinitis (Montpellier)</p></bio><bio xml:lang="en"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of ARIA (Allergic Rhinitis and its Impact on Asthma)</p><p>WHO Collaborating Center for Asthma and Rhinitis (Montpellier)</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Schunemann</surname><given-names>H.J.</given-names></name><name name-style="western" xml:lang="en"><surname>Schunemann</surname><given-names>H.J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of ARIA (Allergic Rhinitis and its Impact on Asthma)</p></bio><bio xml:lang="en"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of ARIA (Allergic Rhinitis and its Impact on Asthma)</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Togias</surname><given-names>A.</given-names></name><name name-style="western" xml:lang="en"><surname>Togias</surname><given-names>A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Akdis</surname><given-names>M.</given-names></name><name name-style="western" xml:lang="en"><surname>Akdis</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of MeDALL (Mechanisms of the Development of ALLergy, Grant Agreement FP7 N°264357, MeDALL paper N°5)</p></bio><bio xml:lang="en"><p>Member of GA2LEN (Global Allergy and Asthma European Network, Grant Agreement FP6)Member of MeDALL (Mechanisms of the Development of ALLergy, Grant Agreement FP7 N°264357, MeDALL paper N°5)</p></bio><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">University Hospital, Department of Respiratory Diseases, Hopital Arnaud de Villeneuve, Montpellier&#13;
Inserm, CESP Centre for research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology team, Villejuif<country>Франция</country></aff><aff xml:lang="en">University Hospital, Department of Respiratory Diseases, HopitalArnaud de Villeneuve, Montpellier&#13;
Inserm, CESP Centre for research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology team, Villejuif<country>France</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Centre for Research in Environmental Epidemiology (CREAL), Barcelona&#13;
Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona&#13;
CIBER Epidemiologia y Salud Publica (CIBERESP)&#13;
Universitat Pompeu Fabra (UPF), Barcelona<country>Испания</country></aff><aff xml:lang="en">Centre for Research in Environmental Epidemiology (CREAL), Barcelona&#13;
Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona&#13;
CIBER Epidemiologia y Salud Publica (CIBERESP)&#13;
Universitat Pompeu Fabra (UPF), Barcelona<country>Spain</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">HO Collaborating Center for Asthma and Rhinitis, Montpellier&#13;
University Hospital of Montpellier — Inserm U657, Hopital Arnaud de Villeneuve, Montpellier<country>Франция</country></aff><aff xml:lang="en">HO Collaborating Center for Asthma and Rhinitis, Montpellier&#13;
University Hospital of Montpellier — Inserm U657, Hopital Arnaud de Villeneuve, Montpellier<country>France</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Department of Clinical Epidemiology &amp; Biostatistics and Medicine, McMaster University, Hamilton<country>Канада</country></aff><aff xml:lang="en">Department of Clinical Epidemiology &amp; Biostatistics and Medicine, McMaster University, Hamilton<country>Canada</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">National Institute of Allergy and Infectious Diseases, Bethesda, Maryland<country>Соединённые Штаты Америки</country></aff><aff xml:lang="en">National Institute of Allergy and Infectious Diseases, Bethesda, Maryland<country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru">Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos<country>Швейцария</country></aff><aff xml:lang="en">Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos<country>Switzerland</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>09</day><month>12</month><year>2015</year></pub-date><volume>8</volume><issue>4</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>6</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bousquet J., Anto J., Demoly P., Schunemann H., Togias A., Akdis M., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Bousquet J., Anto J., Demoly P., Schunemann H., Togias A., Akdis M.</copyright-holder><copyright-holder xml:lang="en">Bousquet J., Anto J., Demoly P., Schunemann H., Togias A., Akdis M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/1238">https://www.pedpharma.ru/jour/article/view/1238</self-uri><abstract><p>Концепции тяжести, активности болезни, ее контроля, восприимчивости к терапии определенно связаны, но, тем не менее, различны. Тяжесть течения обусловлена потерей функций органа, индуцированной патологическим процессом или возникновением тяжелых обострений. Тяжесть может варьироваться с течением времени и нуждается в регулярном наблюдении. Контроль — это степень, в которой в данный момент времени осуществляется лечение симптомов болезни. Концепции для лечения астмы постепенно развивались в виде методических рекомендаций и консенсусов. Целью данной работы является создание единого подхода, представленного ВОЗ, к определению тяжести астмы и других хронических аллергических и сопутствующих заболеваний (ринит, хронический риносинусит, хроническая крапивница, атопический дерматит) для того, чтобы иметь единое определение степени тяжести, риска, контроля, которые можно использовать в клинической практике. В основе этого подхода — адекватный диагноз, наличие и доступность лечения, восприимчивость к лечению, выявление сопутствующих заболеваний и факторов риска. Такой унифицированный подход позволит более точно определить фенотипы тяжелых аллергических (и связанных с ними) заболеваний, что крайне важно для клинической практики, научных исследований (в том числе эпидемиологических), общественного здравоохранения, образования и открытия новых видов лечения. Ключевые слова: IgE, аллергия, тяжесть, контроль рисков, астма, ринит, риносинусит, крапивница, атопический дерматит, SCORAD-шкала тяжести атопического дерматита. </p><p>(Педиатрическая фармакология. — 2011; 8 (4): 6–28)</p></abstract><trans-abstract xml:lang="en"/></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
