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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v11i2.954</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-116</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>НЕДОСТАТОЧНОСТЬ ВИТАМИНА D</article-title><trans-title-group xml:lang="en"><trans-title>VITAMIN D DEFICIENCY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потрохова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Potrokhova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующая кафедрой педиатрии Омской государственноймедицинской академии</p></bio><bio xml:lang="en"><p>PhD, Professor, head of the pediatrics department at the Omsk State Medical Academy</p></bio><email xlink:type="simple">potrochova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соботюк</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobotyuk</surname><given-names>N. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочанцев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bochantsev</surname><given-names>S. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голочалова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golochalova</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шлыкова</surname><given-names>Е. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlykova</surname><given-names>E. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мажукина</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazhukina</surname><given-names>N. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омская государственная медицинская академия Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical Academy of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская детская клиническая больница № 2 имени В.П. Бисяриной, Омск, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bisyarina Municipal Children’s Clinical Hospital № 2, Omsk, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>04</day><month>04</month><year>2014</year></pub-date><volume>11</volume><issue>2</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>30</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Потрохова Е.А., Соботюк Н.В., Бочанцев С.В., Голочалова С.А., Шлыкова Е.Э., Мажукина Н.Г., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Потрохова Е.А., Соботюк Н.В., Бочанцев С.В., Голочалова С.А., Шлыкова Е.Э., Мажукина Н.Г.</copyright-holder><copyright-holder xml:lang="en">Potrokhova E.A., Sobotyuk N.V., Bochantsev S.V., Golochalova S.A., Shlykova E.E., Mazhukina N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/116">https://www.pedpharma.ru/jour/article/view/116</self-uri><abstract/><trans-abstract xml:lang="en"><p>Spread of vitamin D deficiency in children of various ages has not been studied in the Russian Federation. Numerous studies of foreign authors indicate high importance of this issue in many regions of the world, including southern territories with high level of insolation. The review analyzes issues of optimal calcidol level and vitamin D deficiency effect on the immune system. The authors support the hypothesis that vitamin D deficiency results in derangement of congenital and adaptive immunity and may be considered one of the etiological factors of frequent respiratory morbidity in children.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>витамин D</kwd><kwd>дефицит витамина D</kwd><kwd>гипервитаминоз D</kwd><kwd>дети</kwd><kwd>врожденный иммунитет</kwd><kwd>адаптивный иммунитет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vitamin D</kwd><kwd>vitamin D deficiency</kwd><kwd>hypervitaminosis D</kwd><kwd>children</kwd><kwd>congenital immunity</kwd><kwd>adaptive immunity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Неудахин Е. В., Агейкин В. А. Спорные теоретические и практические вопросы рахита у детей на современном этапе. Педиатрия. 2003; 3: 95–98.</mixed-citation><mixed-citation xml:lang="en">Neudakhin E.V., Ageikin V.A. 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