<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ppharm-1116</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВАКЦИНАЦИЯ В СОВРЕМЕННОМ МИРЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>VACCINATION</subject></subj-group></article-categories><title-group><article-title>НОВЫЙ ПОДХОД К ЛЕЧЕНИЮ ОНКОЗАБОЛЕВАНИЙ</article-title><trans-title-group xml:lang="en"><trans-title>NEW APPROACH TO TREATMENT OF ONCOLOGICAL DISEASES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дорофейчук</surname><given-names>В.Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Dorofeichuk</surname><given-names>V.G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потехин</surname><given-names>П.П.</given-names></name><name name-style="western" xml:lang="en"><surname>Potekhin</surname><given-names>P.P.</given-names></name></name-alternatives><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шер</surname><given-names>С.А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sher</surname><given-names>S.A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Нижегородский НИИ детской гастроэнтерологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSI Nizhny Novgorod Research Institute for Children Gastroenterology of the Federal Agency for Healthcare and Social Development</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>07</day><month>12</month><year>2015</year></pub-date><volume>7</volume><issue>4</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>37</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дорофейчук В., Потехин П., Шер С., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Дорофейчук В., Потехин П., Шер С.</copyright-holder><copyright-holder xml:lang="en">Dorofeichuk V., Potekhin P., Sher S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/1116">https://www.pedpharma.ru/jour/article/view/1116</self-uri><abstract><p>Онкозаболевания находятся на втором месте среди причин смертности. Несомненно наличие иммунных нарушений и возникновение ферментного дисбаланса при развитии новообразований. Дефицит эндогенного лизоцима, несмотря на многофакторность развития онкопатологии - одно из важных условий, возникновения и прогрессирования болезни. В статье представлено теоретическое и экспериментальное обоснование для использования лизоцима и антиоксидантных средств в качестве альтернативной терапии онкозаболеваний. Ключевые слова: онкозаболевания, лизоцим, изоантигены, мурамин, свободные радикалы. </p><p>(Педиатрическая фармакология. – 2010; 7(4):37-39)</p></abstract><trans-abstract xml:lang="en"><p>Oncological diseases are the second leading cause of deaths. Immune system disorders and enzymatic imbalances undoubtedly play a role in the development of tumors. Despite the multifactorial nature of oncological pathology development, endogenous lysozyme deficiency is an important condition of a disease nosogenesis. The article provides a theoretical and experimental validation for the use of lysozyme and antioxidant agents as an alternative therapy for oncological diseases. Key words: oncological diseases, lycozyme, isoantigens, muramine, free radicals. </p><p>(Pediatric Pharmacology. – 2010; 7(4):37-39)</p></trans-abstract></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
