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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v12i2.1284</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-10</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕОТЛОЖНЫЕ СОСТОЯНИЯ У ДЕТЕЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EMERGENCY CONDITIONS IN CHILDREN</subject></subj-group></article-categories><title-group><article-title>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ ПО ДИАГНОСТИКЕ СЕПСИСА У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL RECOMMENDATIONS FOR DIAGNOSING SEPSIS IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тепаев</surname><given-names>Р. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Tepaev</surname><given-names>R. F.</given-names></name></name-alternatives><email xlink:type="simple">tepaev@nczd.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научный центр здоровья детей, Москва, Российская Федерация&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Scientific Center of Children’s Health, Moscow, Russia&#13;
Sechenov First State Medical University, Moscow, Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>19</day><month>04</month><year>2015</year></pub-date><volume>12</volume><issue>2</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>205</fpage><lpage>208</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тепаев Р.Ф., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Тепаев Р.Ф.</copyright-holder><copyright-holder xml:lang="en">Tepaev R.F.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/10">https://www.pedpharma.ru/jour/article/view/10</self-uri><abstract><p>Сепсис является одной из ведущих причин летальности детей. Своевременная диагностика ― важнейшее условие успешной терапии сепсиса. В работе представлен анализ рекомендаций по диагностике синдрома системного воспалительного ответа, сепсиса, тяжелого сепсиса и септического шока Согласительной конференции Американского общества торакальных врачей, Общества медицины критических состояний (1992), Международной согласительной конференции педиатров по сепсису (2005), Международной организации «Движение за выживание при сепсисе» (Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012), опубликованых в 2013 г. Освещены современные представления о физиологии системного воспаления при сепсисе и «стерильном» воспалении.</p></abstract><trans-abstract xml:lang="en"><p>Sepsis is one of the leading causes of child lethality. Timely diagnostics is the most important condition for treating sepsis successfully. This study contains analysis of recommendations on diagnosing the syndrome of systemic inflammatory response, sepsis, severe sepsis and septic shock of the Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012,published in 2013. The modern perceptions of systemic inflammation during sepsis and sterile inflammation are highlighted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром системного воспалительного ответа</kwd><kwd>сепсис</kwd><kwd>септический шок</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic inflammatory response syndrome</kwd><kwd>sepsis</kwd><kwd>septic shock</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">American College of Chest Physicians / Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. 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